Frewitt fabrique de machine SA

FREWITT, world leader in powder size reduction technologies, presents FlexMill, an innovative technology combining multiple, milling processes in a single, milling platform dedicated to the pharmaceutical, chemical and food products industries.

MODULARITY – A distinctly avant-garde, modular concept: FlexMill allows you to alternate, depending on your production requirements, between 5 milling heads for size-specific crushing, fine grinding, de-agglomeration, or controlled sifting.

FLEXIBILITY – Incomparable versatility: FlexMill allows you to adapt your milling platform easily and quickly, to suit your current or future production requirements, regardless of your
manufacturing environment or production site.

PERFORMANCE – Enhanced by a factor of 5: FlexMill proves its capabilities with the same degree of flexibility across the entire range of your processing needs, from small batch to
large-scale production.

SAVINGS – Enhanced return on investment and lower cost of ownership: FlexMill integrates three milling processes into a single platform, allowing you to use up to 5 different heads and reduce investment costs by 70%!

The PMV-320 Pin Mill enables users to achieve unprecedented performance while removing all risks encountered during milling. Frewitt proposes a new Gold-Standard in terms of safety for the user: low stable process temperature preserving API-properties, consistent PSD and the elimination of explosion risk in the smallest possible footprint. (PATENT PROTECTED)

USER BENEFITS

Competitors require several footprints, Frewitt needs only one single in-line platform.

• Unique high impact Pin Mill, delivering a PSD range down to D 90 < 6μm
•  Throughput up to 1000kg per hour
•  Compatible for 0/20 ATEX – removal of traditional zone risks due to the process on the vacuum
• Process can be easily contained up to OEB 5

GET MORE FOR YOUR MONEY

A first ever, all in one concept:

• Absence of air flow
• No need of additional cyclone filter or separator
• Reduced product retention
• Easy top-down cleaning
• Reduced product contact surface area
• Less energy consumption
• Shortest product residency time, PSD achieved in one pass.
• API properties remain perfectly protected
• Flexibility of modular arrangement
• Lower operating cost, superior Roi versus competing technologies
• Elimination of noise
• Extremely low process temperature elevation
• Less product retention than competing technologies
• Lowest consumables requirement for this type of process in the market
• Compact assembly for easy in-line integration
• Adaptable to mezzanine or multi-floor executions
• Scalable to Frewitt Lab Scale / Pilot Scale Pin Mill systems
• Best cost / value ratio in the market

Frewitt has reinvented the use of drum inverters. Introducing SMART INVERTER, the only inverter integrated into any milling system without additional equipment required.

SMART INVERTER offers users a unique, two-in-one solution of handling and milling on the same machine, therefore reducing the footprint and investment by half. This new generation of drum inverter enables safe, ergonomic connection/disconnection of drums by a single operator.

Compact in volume, this electrically powered solution has a lift raising the drum, and rotating it into feed position, and proceeding directly to milling and discharging. (PATENT PROTECTED)

USER BENEFITS

While competitors require two separate equipment, the SMART INVERTER performs both functions. The milling head connects directly to the drums, rotating them into position.

Every Frewitt milling process on the Flexmill can be equipped with the Smart Inverter.

A powerful torque rotates the head and up to 100-liter drums with ease. The vertical lift with a 300mm stroke also allows a wide range of drum sizes to be docked . Additionally, the option of Frelift (Frewitt's mobile lifting column) enables users to discharge drums into larger IBC, bag or drum as per user needs.

Competitors currently require minimum two footprints, Frewitt needs only a sole in-line platform, having the following advantages:

• No auxiliary lifting column
• Secure transfer of product into milling chamber
• Dust free
• No physical lifting, the operator's comfort is assured, and his safety guaranteed
• The absence of human intervention makes the process as repetitive as possible
• No change to PSD

The all-in-one version allows a gain in time and efficiency

 The FlexMill-Lab NW is a high-performance bead mill engineered specifically for wet nano milling of pharmaceutical products down to D50 of 50 nanometer.

The modularity of the milling chamber lends itself for processing batches ranging from milligrams of solids up to 1.5 kg. Short milling time at lower specific energy allows a gentle product processing and a tight particle size distribution.

The device’s compact design facilitates easy integration and quick set-up in any laboratory.

THE CHARACTERISTICS OF THE FLEXMILL-LAB NW

• High efficiency mill operating at low rotor tip speed
• Intensification of comminution process, high mixing and homogeneity
• Dynamic separation system (patented) with no filter and thus no clogging
• Optional in-line & real-time PAT solutions for size measurement
• GMP design combining simplicity of use, efficient beads handling and high product recovery
• Easy cleaning Washing-in-Place (WIP) and quick tool-free access to internal components
• Multiple operation modes (batch, semi-batch for filling/ emptying, external recirculation)
• Simple and easy integration of the milling head into a rigid or flexible isolator
• Very broad scope of application for all types of powders
• Milling head readily interchangeable on a single Tri-Clamp connection flange
• Light, compact milling head
• Quick, efficient and simple cleaning of the milling head

For 75 years we have built a solid reputation as a supplier of quality products that meet the specific needs of our extensive customer base. Whether these requirements are in the pharmaceutical, fine chemical or food industry, we offer a complete solution adaptable to the users’ individual environment.

At Frewitt, we are at the forefront in the development of dry and wet milling processes, as well as the manufacturing of customised premium quality mills and installations.

FROM YOUR NEED TO OUR COMPLETE SOLUTION:

At Frewitt, we always aim to fulfil our clients needs and exceed their expectations, which is why we offer fully customised installation solutions for each category of our machines that are adapted to your environment, while still respecting the principles of product and operator protection.

Thanks to our state-of-the-art technological processes we can combine and assemble different modules and various components into a unique installation according to your requirements.

Frewitt Total Care is a complete package; from conception to delivery, we deal with the client directly at each stage of the development process.

SOLUTION PROVIDER:

What sets us apart from our competitors is our ability to assess a clients requirements and, utilizing our wealth of experience in this field, provide a unique package adapted to factors such as a the customers needs, product and work environment. That’s why our turnkey solutions are so successful.

Our advances in technological solutions and processes and our innovative approach to module assembly gives us the flexibility to offer complete solutions with ease and within acceptable time frames.

From cryo to containment to particle size reduction, Frewitt offers a wide variety of unique, high-performance custom installations