Is the API dispersed and homegenically distributed in the polymer matrix?
What is the residence time and what influence does it have on the API?
Is the dosage of the API constant and uniform?
Crystalline or amorphous which is present?
These questions and many more in hot melt extrusion of pharmaceuticals and formulation development can be realized with InSpectro X our UV-Vis inline spectrophotometer in R&D work. It saves enormous time and offers fast data analysis capabilities.
Beside the UV-Vis, we also offer NIR and RAMAN as inline spectrometers for hot melt extrusion with the appropriate fiber optic probes and as „GiANT“ the world’s first „3in1“ spectrometer platform.