Micromacinazione sa offers contract micronization service of APIs (more than 1'000 tons per year) in two separate sites that are regularly inspected by FDA, KFDA, Swissmedic and accredited by Japanese authorities. We have dedicated suites and equipment for HAPIs, steroids, cytotoxic materials, using several high barrier containment systems, to achieve OEL: 0.2mcg per m3 (SMEPAC test).Our engineering team designs constructs and sells jet-mills, barrier containment systems (rigid and flexible isolators) and powder handling systems.micromacinazione sa has expertise in solubility improvement of poorly water soluble APIs, applying innovative technological solutions which include jet-milling mechano-chemical activation, wet milling, Hot Melt Extrusion processes and SCFP technology.
Micromacinazione, founded in 1970 is today the leader in Europe for contract micronization of APIs and HAPIs as well as worldwide supplier of equipment, such as jet mills, glove boxes and pneumatic conveyors.
The company is distributed on 3 sites, two of them dedicated to the micronization service, FDA approved and built according to cGMP rules. The third site is dedicated to the Engineering division, which is foundamental for the mainenance of the 25 installations combining jet mills, glove boxes and pneuatic conveyors, present on the two productions sites. the Engineering division is also involved in the design and production of units, installed into the production department, and specifically designed over single products, for single customers.
The unique feature of Micromacinazione is the combination between the micronization service and the machinery supplier, which makes it being a unique partner for the handling of APIs and HAPIs.
Thanks to the sinergy with the production department, and the continuous feedback received from it, the engineering department has the possibility to design its units according to an end-user point of view. According to this, during the last 40 years, the units, assumed several technical and mechanical advantages, which we are pleased to share with our customer and which can be found either in standard and tailor made units.