Weiss Pharmatechnik GmbH

The closed WIBObarrier® system is a multifunctional and flexible workplace for personnel and product protection. Depending on application the system is usable for transferring, weighing and other handling of high potent pharmaceutical substances and API up to OEB 5. The product area is shielded safety by the front panel. When handling less dangerous substances or for cleaning work the front panel is swung up, so that the WIBObarrier® CCS became an open system. In case of open front, the WIBObarrier® air guidance system guarantees the protection for personnel and clean air quality up to class 5 according to DIN EN ISO 14644-1 in the work area.

The customized configured system is equipped with:

• Two separated working areas for preparation and weighing
• Lateral material locks for inward transfer
• Port with continuous liner for passing out the weighed substances
• Locked front panels
• Compressed air storage in case of onsite drop of compressed air
• Pneumatic lifting device underneath the work surface
• Waste disposal unit in the work area
• Rear wall filter F9/H13 and hood filter H14
• Monitoring equipment for filter and volume flow rate
• WIP system for manual cleaning

WIBObarrier® sytsem with lab containment technology by Glatt. The economical containment solution for labs.

This innovative development in cooperation with the laboratory equipment manufacturer Glatt GmbH, offers a cost-optimized containment solution for processes with different OEB levels in the laboratory sector. The intelligent technology makes it possible to operate several laboratory processes in sequence using only one WIBObarrier® system.

Each lab processing unit or a suitable combination of two processing units is located on a mobile work table, which can be efficiently and flexibly moved into the clean room area if required. This means the clean room zone is significantly minimized and exists only where it is actually needed. A complete process chain for granulation – starting with weighing and proceeding through granulation, milling and drying and on to blending, tableting and coating – can thus be implemented using just one WIBObarrier® system equipped with the LAB Containment Technology by Glatt. The WIBObarrier® system can also be supplemented with a variety of features, depending on OEB level and application case.

The WIBObarrier® open containment system - OCS - is an ergonomic and safe workplace for the protection of persons, products and the environment. As a further development of the WIBObarrier® vertical plus, it combines the WIBObarrier® technology with an additional protection glass panel

for the protection of the personnel. The front panel can be moved horizontally over the entire width of the Barrier and can be used flexibly. The panel is designed as a splash and personal protection. Due to the glove ports, which enable access to the product area, the WIBObarrier® OCS offers an additional protection against cross contamination.

The patented WIBObarrier® air guiding system ensures for the optimum clean-air quality within the product handling area. The vertical clean-air curtain separates the product handling area from the operator area. Clean-air is circulated around the product for an ideal protection. The barrier clean-air curtain pulls the particles from the inside and outside towards the extraction units provided at the front and rear side. The clean-air curtain is held up even if the operator is reaching through it. The detection of contaminants emanated by the emitter can be guaranteed continuously.

• Width: 2,000 mm
• Product exposure < 10µg/m³
• Cleanroom class EN ISO 8
• Robust retention
• Mild air flow, no feeling of draft
• Drum station with lifting column
• Work space for weighing station
• Sliding panel with glove ports
• H14 filter for suspended particles provided in the hood
• Potential integration of exhaust air filters
• Replacement of filter with low contamination potential
• Easy cleaning
• Manufactured according to GMP/FDA guidelines
• Can be provided as explosion proof design

The WIBObarrier® station for filling operations was designed especially for the semi-automatic transferring and filling of pharmaceutical active substances and excipients up to OEB 4. The WIBObarrier® air guidance system guarantees the protection for personnel and clean air quality up to class 5 according to DIN EN ISO 14644-1 in the work area. Even if the front panels are open, for example during cleaning, the stable clean-air curtain ensures the protection of personnel.

The station consists of following components:

• Material lock with roller conveyor
• Transfer cabin with suction lance, handling via glove ports
• Lifting device incl. lifting/tilting function
• Filling cabin with integrated powder transfer system
• Vacuum conveying system of the manufacturer Volkmann
• Container station with containment valve system  according to GMP guidelines for the container
• WIP system for semi-automatic cleaning
• Ports with continuous liner for passing out the emptied packages and parts that have to be cleaned

Weiss Pharmatechnik presents a new product from the field of life science: the WIBObarrier® safety workstation BGKVO 200/170 with an integrated heating and drying cabinet TU 60/60 from Vötsch Industrietechnik. This technology allows intermediate and finished products to be dried on racks in the drying cabinet and processed further under containment conditions in the WIBObarrier®.

The heating and drying cabinet TU 60/60 from Vötsch Industrietechnik was designed for the pharmaceutical industry in line with GMP/FDA. It features short drying cycles, optimised air flow, rapid exchange of air as well as a precisely controlled, homogeneous temperature up to 300 °C in the drying oven.

The WIBObarrier® safety workstation from Weiss GWE is suitable for all areas where increased protection of people and products is required during the handling of pharmaceutical products and active substances. Specially shaped air outlets create a clean air curtain, separating working and ambient areas. A sliding screen with glove access provides additional protection against cross contamination or transmission.

The integrated solution of safety workstation and drying cabinet for drying processes offers the advantage that products can be introduced and processed further under cleanroom conditions. At the same time, the WIBObarrier® air flow system prevents gases or airborne particles emitted by the product from escaping.