Italvacuum s.r.l.

The evolution of the species

CosmoDry System^®. Horizontal paddle vacuum dryer with concentric agitator, fitted with a shaft dismountable in sections, for a maximum ease of cleaning and inspection.

CosmoDry System^® is an innovative horizontal paddle vacuum dryer, the result of highly advanced research by Italvacuum and of a careful analysis of the production requirements of the most demanding customers.

Power, load flexibility, drying speed, easy unloading, maximum quality of dried product. All important and fundamental values, but Italvacuum went even further. The great innovation of CosmoDry System^® as opposed to traditional dryers, in fact, is in the particular structure of the agitator: the inner parts can be dismantled in different parts, quickly and easily. Which means very easy internal cleaning, maintenance and inspection: a mix of qualities that ensure the machine is always kept in perfect working order and optimize the production processes, making CosmoDry System^® also the perfect solution for multi product applications.

CosmoDry System^® is based on an operating philosophy indicated for drying wet powder obtained from the filtering or centrifuge and is suitable for the production of Active Pharmaceuticals Ingredients (API), Fine Chemicals and Intermediates. In addition, an important value that has always been a strong point for Italvacuum: safety. CosmoDry System^® is safe for both the operators and the product, because it is designed and manufactured in compliance with increasingly strict safety standards and in accordance with the cGMP and ATEX regulations.

Powdering while drying

CRIOX System: The only vacuum rotary dryer with electric lump breakers

CRIOX System, a great success patent by ITALVACUUM, is a rotary vacuum dryer able to totally extract water and other solvents from the wet powders coming from filtering or centrifugation.

The central body of the CRIOX System is made of a double cone chamber with a variable speed of rotation, characterized by soft lines without edges and sharp corners. During the system rotation, this structure allows the continuous revolution of the mass and a homogenous and uniform mixing.

Within the drying chamber there are two lump-breaker units with variable speed. During chamber rotation, the lump-breaker group goes alternatively in and out of the product, cleaning itself when not in contact. The lump-breaker groups break at a first stage the possible wet blocks inside the mass and during the drying phase they mill and powder the product.

For bulk products this means an end product ready to be stored, while for the other products this means a correct final particle size distribution. The mechanical action of the chamber and the lump-breaker units allow to increase the surface of the product exposed to evaporation and therefore to carry out the vacuum drying in a very short time and with a temperature on the average much lower than in any other dryer. This is an advantage for the purity of the most delicate thermo sensitive products, as it avoids their degradation. Furthermore the moisture extraction is certainly higher, because the mass core is constantly penetrated by the lump-breaking knives that increase the surface exposed to evaporation.

Lump breakers are electrically operated. CRIOX System is the only rotary double cone dryer of this type currently on the market. This is a crucial feature, as electric motor-driven lump breakers offer exclusive performance and benefits, including:

• Rotating speed control
• Scheduling of operating cycles
• Constant torque with changing speed
• Absorption control
• Ventilated cooling.

Moreover, electric lump breakers ensure:

• Reliability and durability, also in heavy-duty conditions
• Low maintenance.

The total absence of pneumatic circuits avoids the risk of lubricated air pressure release inside the drying chamber and surrounding environment, thereby ensuring utmost safety throughout the production process and the highest quality of dried material.

CRIOX System peculiarity

CRIOX is multi-product allowing its use with the widest range of possible products with crystalline or amorphous structure.

CRIOX is versatile: specific solutions have been studied for the automatic loading and unloading of the product and also for washing, cleaning through and inspecting the plant before changing the type of batch. The SWAB test is also easier to carry out.

CRIOX is multi-purpose: it can also be used as an effective fast blender or homogenizer; in most cases it doesn’t require the subsequent use of the mill and it can also be used as a granulator. It ensures:

• In-cycle adjustable product pulverization without agglomerates
• Perfect homogeneity and uniformity of the dried batch.

CRIOX is completely safe for the operators, the product and the environment, being designed and manufactured according to the highest safety standards for chemical-pharmaceutical productions and in compliance with the even more severe FDA and ATEX norms.

A consolidated ever evolving technology.

Vacuum tray dryers with the MULTISPRAY^® patented fast washing system for complete cleanliness of all inner parts.

Best results, ergonomics, safety and flexibility for any product batch. These are the qualities that have always characterised MULTISPRAY^® vacuum tray dryers, the result of consolidated experience at Italvacuum in the cosmetic, pharmaceutical and chemical industry process applications.

The MULTISPRAY^® vacuum tray dryers consist of a cabinet type chamber and a series of heating plates. Both the chamber and plate surfaces are heated by the circulation of fluid.

Technical characteristics:

• drying surface areas from 0.15 to 32 m²
• C.I.P. MULTISPRAY^® patented fast washing system  
• fluid distribution perfected by a totally uniform temperature
• absolute precision in mechanical processing thanks to the high operating vacuum
• completely smooth geometry and construction and perfect polishing of heating plates for total and easy cleaning, in accordance with the extremely demanding cGMP standards
• minimum surface roughness, rounded edges and maximum internal accessibility
• "particle-free" trays for complete product recovery
• nitrogen diffuser for a uniform flow of gas on every single plate
• heated door as an additional process guarantee
• ready for installation in clean chamber
• airtight door lining
• automatic door opening system

The important added value that differentiates MULTISPRAY^® innovative dryers from conventional systems is that it guarantees total cleanliness of the inner chamber and all heating plates, in compliance with the increasingly restrictive FDA standards and the cGMP standards of good manufacturing. In fact, thanks to the C.I.P. MULTISPRAY^® patented fast washing system, the system can be completely cleaned in just a few minutes, in a repeatable, certifiable way, minimizing washing liquid consumption.

The MULTISPRAY^® vacuum tray dryers can be used in any type of application as there are two versions - fixed plate and removable plate, the latter particularly indicated for multiproduct usage.

Also, for the production of highly active pharmaceutical ingredients (high potency API) and R&D activity, Italvacuum has developed the laboratory version LaboDry.

A revolutionary vacuum drying philosophy

Planex System^®. Multi-patented paddle vacuum dryer with ZeroFriction® planetary movement eccentric agitator.

Planex System^® is the ingenious innovation developed and manufactured by Italvacuum, which brings in a true revolution in vacuum drying technology. A multi-patented machine which is conquering the most demanding operators from all around the world, by guaranteeing results that were unthinkable till now with conventional systems, both horizontal and vertical.

Planex System^® is Italvacuum's special horizontal vacuum paddle dryer with an eccentric agitator featuring two independent movements, allowing it simultaneously revolve around its own axis and rotate tangentially to the drying chamber.

Designed to dry wet feed from filtration and centrifuging processes Planex System^® is ideal for the production of active pharmaceutical ingredients (API), fine chemicals and intermediates.

The combined rotations of the agitator and its small size compared to the drying chamber diameter, ensures the perfect mixing of the entire batch, and allows consuming at least three times less energy than conventional dryers with a concentric agitators. This means a threefold reduction in mechanical and thermal stresses on the batch being dried (1). As a result, even the most delicate and temperature-sensitive products are treated with maximum care.

But there is more. Planex System®, thanks to its agitator’s ZeroFriction^® planetary movement, prevents the product from being rubbed against the drying chamber walls and thus heating up due to friction, a typical problem in conventional paddle systems.

In addition, the rotation of the paddles tangentially to the chamber walls, conveys the product into the small clearance between the agitator and the chamber surface, preventing lumps formation and guaranteeing an even more effective drying and a controlled final particle size distribution, which is impossible to achieve with conventional dryers.

Planex System^® is multi-product, since t can be used with a wide range of products, both with crystalline and amorphous structure. In addition, thanks to the agitator movement controlled by the “Stop & Swing” program, it is also ideal for drying small batches.

Planex System^® is versatile, because it drastically reduces the downtime needed to rearrange the line, wash, clean and inspect the system before switching production processes. This is an important added-value, as it makes it fast and easy to pass from one production run to another.

Planex System^® is safe for operators, the environment and the product, because it is designed and manufactured in compliance with European Union ATEX Directives and CE marking requirements, as well as with the increasingly stringent US FDA standards and cGMP Current Good Manufacturing Practice Regulations.

(1) Analysis by Politecnico di Torino’s Department of Materials Science and Chemical Engineering

When others stop, Saurus939 carries on.

The vacuum pump unique in reliability, performance and consumption.

Saurus939 has all the Italvacuum experience, a vacuum pump that guarantees unrivalled performance in all the main chemical and pharmaceutical processes, ensuring total recovery of extracted solvents, even in severe operating conditions.

A simply designed machine, that combines traditional robustness and reliability with the most evolved technology.

Resistance, strength and consumption of oil virtually eliminated thanks to the innovative LubriZero^® system. A solution which guarantees perfect operation and optimum results with total respect for the environment.

Saurus939 has no fear of aggressive and corrosive solvents, powders and condensates, nor distillation by-products. But above all it does not fear confrontation because it is designed and manufactured to work 24 hours a day with a constant excellent performance and minimum operating costs, thanks to a low-energy motor, negligible oil consumption and easy, immediate maintenance.

Powerful, efficient, but absolutely safe: Saurus939 guarantees optimum safety through the whole process and complete purity of the final product. In other words, ensures an uncontaminated vacuum.

Saurus939 also complies to ATEX norms.