26 - 28 September 2017 // Nuremberg, Germany

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Zoom product LOGO_FrymaKoruma Dinex - Vacuum processing unit for the cosmetics and pharmaceutical industries

FrymaKoruma Dinex - Vacuum processing unit for the cosmetics and pharmaceutical industries

LOGO_FrymaKoruma Dinex - Vacuum processing unit for the cosmetics and pharmaceutical industries

FrymaKoruma Dinex - Vacuum processing unit for the cosmetics and pharmaceutical industries

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The FrymaKoruma Dinex is the proven system of choice for the production of creams, lotions, gels, ointments, toothpaste and other kinds of dispersion. The special requirements that must be satisfied for the manufacture of parenteral, pulmonary, peroral and percutaneous dosage forms are met by the Dinex machine and associated automation concept in every respect. This concept is based on an external process tool with recirculation and provides an ideal platform for precise processing of products spanning a very wide viscosity range.

At the heart of the system is a rotor-stator homogenizer, which is mounted underneath the process vessel and connected to its top part by a recirculation line (long loop). This configuration ensures that all ingredients pass through the homogenizer at least twice before being discharged, because ingredient materials are introduced through the running homogenizer. The homogenizer also incorporates the internal pumping function for circulating and discharging the products and cleaning the machine. The new homogenizer – which significantly improves the Dinex' performance – is a particularly exciting innovation.

The scraper agitator supports the top-down macro-mixing of the product in the vessel that is produced by the long-loop recirculation line. At the same time, it guarantees optimal thermal transfer between the vessel wall and the product during the heating and cooling cycles. The recirculation line can optionally be branched into the conical bottom section of the process vessel while the machine is operating. This short loop permits batch sizes with a larger variability and allows foaming products to be circulated underneath the surface.

Like the processing unit, the automation concept has a modular architecture that leaves nothing to be desired. Three basic concepts are possible according to the individual requirements of the application. Various modules and functions can be controlled and integrated, depending on the concept selected.

The Dinex is offered in two different versions, to enable the vacuum processing unit to be aligned to each customer's specification:

•The Dinex V has a vertically mounted homogenizer, which can be operated in dispersion or pumping mode, depending on the position of the stator. In order to switch between shear-intensive and shear-free operation in this way, the rotor and stator have to be moved apart. At the same time, a defined shear energy input can be optimized and monitored thanks to the precise speed control.

•The Dinex H features a horizontal homogenizer arrangement. The shear energy can be varied within a defined range by adjusting the speed. The pumping efficiency of the process tool changes proportionally. The horizontal design facilitates high powder feed rates and a lower machine height.

Standard version

•Pressure vessel with safety device and scraper agitator

•Powerful vacuum system

•Rotor-stator homogenizer with integrated pumping function

•Double-jacket for heating and cooling with insulating jacket

•Temperature control

•User friendly control/visualization

•External recirculation line (long or short loop)

•Full CIP capability


•Vertical or horizontal homogenizer arrangement

•Counter-rotating agitator

•Shaft seal or mechanical seal concepts

•Lid lifting device

•Three automation levels and additional modules

•Load cells and dosing units

•Comprehensive validation documentation

•ATEX / US-EX compliance

•Sterile versions

•Other options on request


•Lotions, creams, gels

•Ointments, pastes, syrups


•Decorative cosmetics

•Haircare products

Key benefits

•Shorter batch cycles◦Rapid feeding of dry materials

◦Efficient homogenizer with shear energy optimization

◦Defined homogenizing passages

◦Optimal control and monitoring of droplet size and distribution

◦Circulation of foaming products underneath the surface

•High reproducibility

◦Recipe controlled production

◦Excellent cleaning and sterilization characteristics

•Lower operating costs◦Large variability in batch sizes

◦Fast creation of emulsions

Text for the blue box: The NEW Dinex homogenizer

•has a 10% better shear rate,

•produces smaller droplets (D50 value <= 300 nanometres) and a narrower particle size distribution,

•introduces less heat into the product,

•achieves optimal emulsion results faster.

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